A.J. Robison on the Neural Basis of Sex Differences in Depression – #37

Corey and Steve talk with MSU Neuroscientist A.J. Robison about why females may be more likely to suffer from depression than males. A.J. reviews past findings that low testosterone and having a smaller hippocampus may predict depression risk. He explains how a serendipitous observation opened up his current line of research and describes tools he uses to study neural circuits. Steve asks about the politics of studying sex differences and tells of a start up using CRISPR to attack heart disease. The three end with a discussion of the psychological effects of ketamine, testosterone and deep brain stimulation.

Jason Snyder on Neurogenesis – #24

Steve and Corey talk to Jason about a fundamental question of neuroscience: Do humans grow new neurons as adults? The dogma that humans do not, gave way to the dogma that they do, which is now being questioned. Adult neurogenesis has been associated with learning, better cognitive function and resistance to depression. Jason suggests that a simple error of treating young mice as models for adult humans led to excessive optimism regarding the potential for later neuronal growth. Recent findings suggest that adults grow few, if any, new neurons but that what little neurogenesis occurs can probably be enhanced by exercise.

Jason Snyder on Neurogenesis – #24

Steve and Corey talk to Jason about a fundamental question of neuroscience: Do humans grow new neurons as adults? The dogma that humans do not, gave way to the dogma that they do, which is now being questioned. Adult neurogenesis has been associated with learning, better cognitive function and resistance to depression. Jason suggests that a simple error of treating young mice as models for adult humans led to excessive optimism regarding the potential for later neuronal growth. Recent findings suggest that adults grow few, if any, new neurons but that what little neurogenesis occurs can probably be enhanced by exercise.

Transcript: Jason Snyder on Neurogenesis – #24

Steve: Thanks for joining us. I’m Steve Hsu. Corey: And I’m Corey Washington and we’re your hosts for Manifold. Corey: Our guest today is Dr. Jason Snyder, Assistant Professor of Psychology and member of the Center for Brain Health at the university of British Columbia. Corey: Jason’s research focuses on neurogenesis and specifically how hippocampal […]

Transcript: Bobby Kasthuri & Brain Mapping – Episode #2

Corey: All right. Okay. Welcome to our podcast. My name’s Corey Washington, and this is my co-host Steve Hsu. And we’re going to tell you little bit about how we hope our next episode should be going and some of the plans we’ve got for the show, but we’d like to lay out our general […]

Bobby Kasthuri & Brain Mapping – Episode #2

Corey and Steve are joined by Bobby Kausthuri, a Neuroscientist at Argonne National Laboratory and the University of Chicago. Bobby specializes in nanoscale mapping of brains using automated fine slicing followed by electron microscopy. Among the topics covered: Brain mapping, the nature of scientific progress (philosophy of science), Biology vs Physics, Is the brain too complex to be understood by our brains? AlphaGo, the Turing Test, and wiring diagrams, Are scientists underpaid? The future of Neuroscience.

Bobby Kasthuri & Brain Mapping – Episode #2

Corey and Steve are joined by Bobby Kasthuri, a Neuroscientist at Argonne National Laboratory and the University of Chicago. Bobby specializes in nanoscale mapping of brains using automated fine slicing followed by electron microscopy. Among the topics covered: Brain mapping, the nature of scientific progress (philosophy of science), Biology vs Physics, Is the brain too complex to be understood by our brains? AlphaGo, the Turing Test, and wiring diagrams, Are scientists underpaid? The future of Neuroscience.